Parry-Romberg Syndrome (PRS) is an atypical condition characterized by hemiatrophy of the face.Despite its rarity, the precise pathophysiological processes underlying its etiology remain elusive.While previous reports have hinted at the potential involvement orange zinger tomato of autoimmune factors, our case report aims to explore a novel perspective.Specifically, we pose the question click here of whether multiple sclerosis (MS) could be a plausible causative factor for PRS.Additionally, we investigate the potential association between Radiologically Isolated Syndrome (RIS) and the development of Parry-Romberg Syndrome.